How We Think About Immune Engineering
Perspectives on cancer escape, immune response, and the principles behind multispecific immunotherapies — from the scientists and engineers building FORGE at Coding Bio.
Clinical Context
From serums to T-cell engagers: how immunotherapy learned to direct the immune system.
A century of immunotherapy — from Coley's toxins to checkpoint inhibitors to programmable multispecifics. Each era solved one problem and revealed the next.
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Same target, different outcome.
Multiple approved therapies target the same myeloma antigen. They do not perform the same. The variable is not the target — it is what was measured during design, and whether those measurements predicted the biology that determines clinical outcomes.
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